1316 Serum Ykl-40 and Assessment of Asthma Severity in Egyptian Children
نویسندگان
چکیده
منابع مشابه
the relationship between serum ykl-40 levels and severity of asthma.
ykl-40 (chitinase-3-like-1) has been introduced as a marker of inflammation in asthma. the aim of this study was to determine the role of ykl-40 in asthma and to evaluate the relationship between ykl-40 and asthma severity. in the study, 60 non-smoker asthma patients without additional diseases (aged between 20-60 years, female: 34) were grouped [group i: well controlled asthma patients (n: 30)...
متن کاملThe relationship between serum YKL-40 levels and severity of asthma.
YKL-40 (chitinase-3-like-1) has been introduced as a marker of inflammation in asthma. The aim of this study was to determine the role of YKL-40 in asthma and to evaluate the relationship between YKL-40 and asthma severity.In the study, 60 non-smoker asthma patients without additional diseases (aged between 20-60 years, female: 34) were grouped [Group I: Well controlled asthma patients (n: 30),...
متن کاملSerum YKL-40: A possible biomarker in bronchial asthma?
Background: The evolutionary conserved 18 glycosyl hydrolase family contains chitinases and chitinase like proteins that share amino acid sequence homology with true chitinases but lack enzymatic activity. The chitinase like protein YKL-40, encoded by the chitinase3-like 1 gene (CHI3L1), has been found to be either the cause or a biomarker for asthma. However, its pattern of expression with dis...
متن کاملSerum levels of IL-17A increase in Asthma but not in accordance with Serum level of IgE and Asthma Severity
Background and Aims: Recent evidence suggests that T helper (Th) 17 cells are involved in the emergence of asthma. Th17 cells have a key role in inducing inflammation in asthmatic airways thus Interleukin (IL)-17A, the main cytokine of Th17, contributes to airways inflammation. Materials and Methods: We evaluated the level of IL-17A and total immunoglobulin E (IgE) in sera of 100 asthmatic p...
متن کاملEffect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
BACKGROUND The chitinase-like protein YKL-40 is involved in inflammation and tissue remodeling. We recently showed that serum YKL-40 levels were elevated in patients with asthma and were correlated with severity, thickening of the subepithelial basement membrane, and pulmonary function. We hypothesized that single-nucleotide polymorphisms (SNPs) that affect YKL-40 levels also influence asthma s...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2010
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-201011001-01316